The Cognitive Neuroscience Laboratory (CNL) is a multidisciplinary research laboratory that studies the neural underpinnings of human behavior primarily using magnetic resonance imaging (MRI). Our two focus areas are cognition in the setting of sleep deprivation, and the cognitive neuroscience of aging. In addition to our own research, we support a number of other investigators.

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Upcoming study

In Nov/Dec of 2014, we will be conducting a research project that aims to study the effects of sleep on cognitive functions in adolescents in Singapore. My team and I would like to invite you to partner with us in this endeavour.

(1) to examine the impact of short sleep on cognitive function
(2) to investigate the effectiveness of extending sleep opportunity as an intervention to reduce cognitive impairments induced by sleep loss

Scientific importance:
This will be the first study of its kind, and we believe that its findings regarding sleep and health will be of use to educators and schools.

If you are between 15-19 years old, or know of anyone who would like to participate in this study, please download the FAQ sheet to learn more about the study.

Dates: 26 Nov ⎯ 9 Dec 2014
Venue: Nanyang Girls Boarding School
Vacancies: 60
Eligibility: 15-19 years and healthy
Cost: $0

What you can expect:

  • Have first-hand experience of various research techniques
  • Attend talks by scientists in various fields of research
  • Know how your brain looks like and how well you sleep

If you have any additional questions or clarifications, feel free to send your enquires to Miss Ruth Leong at or call the Cognitive Neuroscience Laboratory (CNL) at 6516 4457 during office hours.


On this World Sleep Day (14 March '14), Prof Michael Chee comments on 'why getting enough sleep matters'.

Click here to read more.


Talking About The Walk With Singaporean Clinician Scientists

In this series, we follow the career journeys of Dr Michael Chee, Dr Ong Sin Tiong,
Dr Tai E-Shyong, and Dr Ooi Eng Eong.

Click here to read more and for links to the videos.




1 July 2014


The mechanisms of how sleep loss may result in altered brain structure and cognition remain unknown. We investigated the contribution of sleep duration and quality to age-related changes in brain structure and cognitive performance in relatively healthy older adults. [Download Article]

28 May 2014


Human sleep schedules vary widely across countries. We investigated whether these variations were related to differences in social factors, Morningness–Eveningness (ME) preference, or the natural light–dark cycle by contrasting the sleep duration and timing of young adults (age: 18–35 years) on work and free days in Singapore (n=1898) and the UK (n=837). [Download Article]

1 April 2014


To investigate the effects of post-­learning sleep and sleep architecture on false memory in healthy older adults. A false memory was induced using the Deese-­Roediger-­McDermott (DRM) paradigm and assessed following nocturnal sleep and following a period of daytime wakefulness. Post-­learning sleep structure was evaluated using polysomnography (PSG). [Download Article]

8 March 2014


Previous research suggests that sleep deprivation may heighten normal reactions to an aversive social encounter. In this study, we explored how 24 h of sleep deprivation may influence responses to ostracism. Ninety-six healthy young adults were randomly allocated to either the sleep-deprivation or well-rested condition, wherein they engaged in two rounds of a ball-tossing game (Cyberball) programmed so that they would be included or ostracized. [Download Article]

25 January 2014


Object recognition becomes impaired at faster presentation rates and here we show the neuroanatomical foci of where this might be exacerbated by sleep deprivation (SD). Twenty healthy human participants were asked to detect a target house in serially presented house pictures that appeared at 1–15 images/s. Temporal response profiles relating fMRI signal magnitude to presentation frequency were derived from task-responsive regions. [Download Article]





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