The Cognitive Neuroscience Laboratory (CNL) is a multidisciplinary research laboratory that studies the neural underpinnings of human behavior primarily using magnetic resonance imaging (MRI). Our two focus areas are cognition in the setting of sleep deprivation, and the cognitive neuroscience of aging. In addition to our own research, we support a number of other investigators.

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CNL at the 6th World Congress on Sleep Medicine (WASM 2015)

Professor Chee presented
Functional Imaging of Sleep Loss
at the symposium


Dr Lo gave an oral presentation on
Associations between Self-Resported
Sleep Duration and Cognitive Performance in Older Adults: A Systematic Review
and Meta-Analysis
Ms Leong presented a poster titled
Self-Reported Sleep Duration and Levels of Inflammatory Markers: Similarities and Differences across Genders


Functional Imaging of Sleep Loss
At the 6th World Congress on Sleep Medicine (WASM 2015) held in Seoul, Korea, Professor Chee reviews functional imaging research to date to understand what and why cognitive domains are impaired by sleep loss.

Slides to his talk can be found here.


Sleepless in Singapore
What is the lack of sleep costing us in terms of our work and our health? In this session, Professor Chee shares his expertise in sleep and cognition.

Click here to read more.


Aged to Perfection
Professor Chee gives us some tips on how we can stay sharp as we age.

Click here to read more.


Train Your Brain
We partner with Channel News Asia again - this time on the neural processes of aging.

Click here to read more.


On this World Sleep Day (14 March '14), Prof Michael Chee comments on 'why getting enough sleep matters'.

Click here to read more.



17 February 2015


Significant inter-individual differences in vigilance decline following sleep deprivation exist. We characterized functional connectivity in 68 healthy young adult participants in rested wakefulness and following a night of total sleep deprivation. [Download Article]

1 January 2015


Pathogenic effects of stress show interindividual variation and may be influenced by situational variables such as sleep loss. Here, we probed how the sympathetic nervous system might contribute to altered reactivity in sleep deprived persons. [Download Article]

23 September 2014


The association cortex supports cognitive functions enabling flexible behavior. Here, we explored the organization of human association cortex by mathematically formalizing the notion that a behavioral task engages multiple cognitive components, which are in turn supported by multiple overlapping brain regions. [Download Article]

1 July 2014


The mechanisms of how sleep loss may result in altered brain structure and cognition remain unknown. We investigated the contribution of sleep duration and quality to age-related changes in brain structure and cognitive performance in relatively healthy older adults. [Download Article]

28 May 2014


Human sleep schedules vary widely across countries. We investigated whether these variations were related to differences in social factors, Morningness–Eveningness (ME) preference, or the natural light–dark cycle by contrasting the sleep duration and timing of young adults (age: 18–35 years) on work and free days in Singapore (n=1898) and the UK (n=837). [Download Article]


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