Dr. Michael Chee
michael.chee at
duke-nus.edu.sg


Professor/Principal
Investigator

 

Dr. Michael Chee is a Professor at Duke-NUS Medical School and Principal Investigator of the Cognitive Neuroscience Lab. He is a member of the Neuroscience and Behavioral Disorders Program at Duke-NUS Medical School.

Dr. Chee earned a MBBS from the National University of Singapore and trained in internal medicine and neurology. He was a Fellow in Epilepsy and Clinical Neurophysiology at The Cleveland Clinic Foundation in Ohio, USA and after some years in clinical practice, undertook a research fellowship at the Massachusetts General Hospital NMR Center in Boston.

His early research using functional magnetic resonance imaging (fMRI) involved several seminal contributions in the study of the bilingual brain, specifically the study of English-Chinese bilinguals. Intrigued by the effects of numerous trans-meridian flights he had taken, he began studying cognition in the setting of short-term total sleep deprivation - a research area that has been his principal focus since 2003. The goals of this research are to uncover the cognitive weak links contributing to performance decline in the sleep-deprived state and to examine the basis for inter-individual variation in tolerance of sleep deprivation. Two areas of his current interest are the effects of sleep deprivation on visual attention and processing capacity, and on decision-making.

In addition to sleep deprivation research, Dr. Chee investigates healthy brain aging in the elderly population. Since 2005, his lab has been following a cohort of healthy elderly volunteers using structural brain imaging, neuropsychological tests and a battery of blood markers with a view to characterize healthy cognitive aging in a cohort of ethnic Chinese. This aging study is currently the only one in East Asian followed up using brain imaging.

Dr. Chee has served on the program committee of the Organization for Human Brain Mapping. He is on the editorial boards of Sleep, Neuroimage and Frontiers in Sleep and Chronobiology and has been the recipient of research support from The Shaw Foundation, Biomedical Research Council, Defense Science and Technology Agency, National Medical Research Council, and National Institutes of Health (US) and Glaxo Smith Kline PLC. Among his awards are the SingHealth Investigator Excellence Award (2004), the inaugural Singapore Translational Research Investigatorship (STaR) and the National Outstanding Clinician-Scientist Award (2009).

 
 
 
Post Doctoral Fellows
 

Ong Ju Lynn
julynn.ong at
duke-nus.edu.sg

 

I'm interested in applications of image processing and pattern recognition in medical contexts. Being able to 'see through' the body using different imaging modalities to aid diagnosis and a better understanding of anatomy and physiology presents a never-ending series of exciting research questions. I previously worked on methods for polyp detection in CT colonography and am now trekking the pathways of fMRI and cognitive neuroscience.

I am also a bit of a photo junkie (anything from a blue sky to a crawling snail) for lots more freestyle image processing!

 
 

Stijn Massar
stijn.massar at
duke-nus.edu.sg

 

As a work and organizational psychologist, I am interested in how our brains enable us to do our daily jobs. As a neuroscientist, I am interested in how real life situations can inform us about our cognitive organization and brain functions.

During my undergraduate and PhD work at the universities of Nijmegen and Utrecht in the Netherlands, I have studied how cognitive and motivational functions can be affected by the state of mental fatigue induced by long periods of work. I have also studied how rewards and threats can guide cognitive functions such as learning and attention.

In Dr. Michael Chee’s lab, I am continuing the line of research on sleep deprivation and decision-making that has been initiated in collaboration with Dr. Scott Huettel’s group at Duke University.

 
 

James Cousins
james.cousins at
duke-nus.edu.sg

 

Why do we sleep? This profound alteration in consciousness and brain activity remains one of the most intriguing unsolved questions in biology.

There is now compelling evidence that memories are replayed during sleep, which serves to stabilize, enhance and integrate memory traces within existing networks. The reorganizing properties of sleep may be critical to adapt newly learned information and maximize its utility to direct future behavior. My research aims to uncover the many ways in which memories are transformed during sleep.

My PhD research at the University of Manchester in England used a technique of reactivating memory traces during sleep by replaying sounds associated with learning. Currently I am developing new paradigms that utilize this method to explore the role for reactivation in spatial memory, problem solving and creativity. My work also takes advantage of modern neuroimaging techniques such as fMRI and EEG, which offer a unique opportunity to peer inside the previously hidden world of sleep.

 
 

Elaine van Rijn
elaine.van.rijn at
duke-nus.edu.sg

 

I’m interested in the effect of sleep on learning and memory. During my PhD at Swansea University in the United Kingdom my researched focused on the relationship between sleep and memory consolidation, and whether the content of dreams reflects this ongoing process. Here at CNL I’m extending my research on sleep-dependent memory consolidation. My work looks at whether a period of sleep is more beneficial for learning and memory than an equal period of wakefulness. I’m also examining if certain types of memories are consolidated preferentially during sleep, and whether we can influence which memories undergo consolidation, for example through the use of reward.

 
 
 
Image Analysis and Methods Team
 

Jesisca Tandi
jesisca.tandi at
duke-nus.edu.sg

 

In this lab, my main task is to support the lab with issues related to fMRI image preprocessing and analysis.

My main interest is related to image processing and analysis, especially in MRI. More specifically, I like to think about how to improve currently available methods, to make it better in terms of accuracy and efficiency.

 
 
 
Sleep Team
 

Nicholas Chee
nick.chee at
duke-nus.edu.sg

 

I am a research assistant for the sleep team. My responsibilities in the lab include recruiting subjects, conducting experiments involving MRI scans and polysomnography, and assisting with data analysis. Additionally, due to my height, I am the lab’s self-propelled stepladder. My research interest is in the modulation of memory, such as the enhancement of memory via brain stimulation. In the pursuit of understanding how the brain functions, I view the experimental manipulation of brain physiology to produce tangible changes in cognitive function as the clearest proof of understanding.

Outside the lab, I pursue mountaineering, and am constantly aiming for new, more technical climbs in distant peaks around the world. There is nothing comparable to pushing oneself on the snow-covered slopes of mountain high above the clouds.

 
 

Teo Teck Boon
teckboon.teo at
duke-nus.edu.sg

 

As a research assistant for the sleep team, my responsibilities in the lab include conducting experiments involving MRI scans and polysomnography, recruiting subjects, and assisting with data collection. Above all this, I get to learn new things about the brain all while utilising the MRI scanner which has always appeared in textbooks and during undergraduate studies!

During my free time, I like to participate in a wide spectrum of activities from high intensity sports (especially soccer), to relaxing activities like playing the piano, watching movies and spending time with family. It is also my dream to travel the world especially to UK (Manchester), Europe and USA.

 
 

Shirley Koh
shirley.koh at
duke-nus.edu.sg

 

As a research assistant in the CNL sleep team, my main responsibilities involves assisting the post docs with their research work. This includes participant recruitment, conducting sleep deprivation experiments, data collection and helping out with analyses. Apart from these, through regular regular journal article readings, highly encouraged by our post docs, I get to learn new things about neruoimaging and cognition everyday that one cannot simply get just by reading the textbook. My interest lies in understanding more about the human brain, more specifically, music and cognition and how these can be affect by sleep.

In my free time, I enjoy dancing ballet, watching films, learning more about the start up world and of course, travelling the world.

 
 

Ksenia Vinogradova
ksenia at
duke-nus.edu.sg

 

My responsibilities include the usual sleep team RA duties, namely - conducting briefings, data collection and analysis for the experiments involving fMRI and polysomnography, as well as for purely behavioural ones. In addition, I also do programming, in particular, web programming for the lab. I am very enthusiastic about all things neuroscience, but my main interests lie in the fields of memory, sleep and psychiatric disorders.

Apart from science, I love heavy music, books (both fiction and non-fiction), films and travelling. My life goal is to visit all the (recognised) countries in the world.

 
 

Andrew Roshan Dicom
andrew.dicom at
duke-nus.edu.sg

 

I have both psychology and aerospace engineering backgrounds in terms of my education. My interests lie mainly in the effects of sleep on learning and memory. As a research assistant in the CNL sleep team, my duties include data collection (which involves the use of EEG and fMRI), helping with data analyses, other administrative duties, as well as constantly updating my skill set and expanding my knowledge base.

My hobbies include reading a wide range of history related books, the works of JRR Tolkien and others. I do also like traveling to different countries.

 
 

Shamsul Azrin Bin Jamaluddin
shamsul.jamaluddin at
duke-nus.edu.sg

 

I am a research assistant at the CNL under the sleep team. My duties in the lab include collecting and analyzing behavioral, PSG, and fMRI data. Broadly, I am interested in the role of sleep in learning and memory, specifically in terms of how oscillations support these processes. Prior to joining the lab I completed an MSc in Cognitive Neuroscience at UCL.

Outside of work I enjoy listening to podcasts and practicing yoga.

 
 

Lau Te Yang
teyang.lau at
duke-nus.edu.sg

 

I am a research assistant in the sleep team. My responsibilities include collecting and analyzing fMRI, PSG, and behavioral data from sleep experiments. Before joining the lab, I graduated with a BA Honours in Psychology from Flinders University. During that time, I developed an interest in sleep and circadian research, specifically the effects of circadian misalignment (e.g., social jetlag, night shift work) on our daily functioning as well as ways (e.g., naps) to alleviate the negative effects of sleep deprivation.

I enjoy playing football, watching films and reading books during my free time and diving when I have the opportunity. I also love to travel around the world and experience different cultures.

 
 
 
Aging Studies Team
 

Alyssa Ng
alyssa.ng at
duke-nus.edu.sg

 

I studied Psychology and Economics at the University of Melbourne and graduated in 2016 with a BA honours in Psychology. During my time in university, I developed an interest in neuropsychology research, especially in the neuroimaging methods they utilised such as fMRI and EEG. My interests broadly include topics of consciousness, computational models of decision-making, psychiatric disorders and cognitive impairment in elderly populations. As a research assistant in the lab, my duties include data collection and analyses, and apart from these my work allows me to constantly encounter new opportunities for myself to expand my knowledge and skill set.

In my free time, I like to read science fiction books, dabble in digital art and practise yoga.

 
 
 
Secretary
 

Shirley Kok
shirley.kok at
duke-nus.edu.sg

 

I provide secretarial services and administrative support to Dr. Michael Chee and the lab. Efficiency is my middle name!

Part of my daily routine includes having afternoon tea. My day at work will not be complete without it.

 
 
 
Graduate Student
 

Ruth Leong

 

My research focuses on age-related changes in brain and cognitive function. In particular, I am interested in the role of sleep in memory consolidation, and how this process may be altered in older adults. In my free time, I enjoy the company of my two frisky dogs and one very cheeky parrot.

 
 

Hosein Aghayan Golkashani

 

As an MD-MPH I have always been interested in interdisciplinary research in educational neuroscience. I also consider sleep deprivation a major public health problem that has not been sufficiently addressed.

My research focuses on how new memories are integrated into existing cognitive frameworks. I mainly investigate neurobiological mechanisms involved in consolidation of schema congruent memories in different stages of sleep. I am also interested to study how these processes could be altered in a sleep deprived brain.

 
 
 
Scanner Operator
 

Annalissa Tiu Munoz
annalissa at
duke-nus.edu.sg

 

I'm the scanner operator who's the most sleep-blest (or bliss) of the rest. I'm a lark whose main work is in providing daytime support in MRI operation.

I'm a chaplain's wife with two lovely children, a Mac Air, a Nespresso and a Kindle.

 
 
 
 
         


Aiqing Ling
Amiya Patanaik
Annette Chen
Bindiya Raghunath
Camilo Libedinsky
Cher Weishan
Chong Shin Wee
Christopher Asplund
Chun Siong Soon
Cindy Goh
Delise Chong
Deepti Mulick
Emily Koh
Enhui Yong
Grace Tang
Hweeling Lee
Irma Kurniawan
Jack De Havas
Jean Liu
June Lo
Jiat Chow Tan
Jingwei Lim
Joann Poh
Joshua Goh
Julian Lim
Karen Chan
Karen Sasmita
Karren Chen
Kavitha Dorairaj
Kong Danyang
Lee Su Mei
Lee Xuan Kai
Lisa Chuah
Loh Kep Kee
Lydia Teo
Mei-fen Yang
Meiyi Ngeow
Michele Veldsman
Ming Yi Zhou
Nabilah Mohammad
Natalie Wee
Pearlynne Chong
Poh Jia Hou
Praneeth Namburi
Sam Sim
Sarayu Parimal
Sei Hwan Oh
Siti Yaakub
Shuhui Yau
Shuwei Koh
Sunny Kort
Thomas Yeo
Tiffany Chia
Vanessa Chen
Vaisakh Puthusseryppady
Vinod Shanmugam
Vinod Venkatraman
Vivian Isaac
Weiyan Chee
William Rekshan
Ying Lee
Zheng Hui
Zhu Wan Zheng

       
 



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